Requirement for Leukotriene B4Receptor 1 in Allergen-induced Airway Hyperresponsiveness

Volume: 172, Issue: 2, Pages: 161 - 167
Published: Jul 15, 2005
Abstract
Rationale: Leukotriene B4 (LTB4) is a rapidly synthesized, early leukocyte chemoattractant that signals via its cell surface receptor, leukotriene B4 receptor 1 (BLT1), to attract and activate leukocytes during inflammation. A role for the LTB4–BLT1 pathway in allergen-induced airway hyperresponsiveness and inflammation is not well defined. Objectives: To define the role of the LTB4 receptor (BLT1) in the development of airway inflammation and...
Paper Details
Title
Requirement for Leukotriene B4Receptor 1 in Allergen-induced Airway Hyperresponsiveness
Published Date
Jul 15, 2005
Volume
172
Issue
2
Pages
161 - 167
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