EFFICACY AND SAFETY OF ENZYMATIC POSTERIOR VITREOUS DETACHMENT BY INTRAVITREAL INJECTION OF HYALURONIDASE

Purpose: To investigate the efficacy and safety of intravitreal injection of hyaluronidase in producing liquefaction resulting in a posterior vitreous detachment. Methods: Fifteen young pigmented rabbits were randomized into 3 groups that received 5 (group 1), 10 (group 2), or 20 (group 3) IU of hyaluronidase. The fellow eyes were injected with a volumetric equivalent dose of balanced salt solution as control. The rabbits were followed for 9...