POI06 Rituximab in neuropsychiatric systemic lupus erythematosus: a retrospective study of the Cambridge experience

The monoclonal B cell depleting antibody, rituximab, has shown promise in open-label studies of refractory neuropsychiatric (NP) lupus. Here, we show our tertiary referral centre experience in patients with CNS syndromes probably causally related to active SLE, and in those with past CNS symptoms treated for non-NP SLE. Consensus criteria proposed by Hanly et al (Arth Rheum 2007) were used to classify patients into those likely to have...