Iron deficiency accelerates Helicobacter pylori–induced carcinogenesis in rodents and humans
Volume: 123, Issue: 1, Pages: 479 - 492
Published: Dec 21, 2012
Abstract
Gastric adenocarcinoma is strongly associated with Helicobacter pylori infection; however, most infected persons never develop this malignancy. H. pylori strains harboring the cag pathogenicity island (cag+), which encodes CagA and a type IV secretion system (T4SS), induce more severe disease outcomes. H. pylori infection is also associated with iron deficiency, which similarly augments gastric cancer risk. To define the influence of iron...
Paper Details
Title
Iron deficiency accelerates Helicobacter pylori–induced carcinogenesis in rodents and humans
Published Date
Dec 21, 2012
Volume
123
Issue
1
Pages
479 - 492
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