Preparation and Formulation of a Human Chorionic Gonadotropin Antifertility Vaccine: Selection of Adjuvant and Vehicle*

: Peptides representing sequences of the beta subunit of HCG (Cys‐(Pro) 6 ‐111–145 and 109–145) were coupled to tetanus toxoid (TT) and the resultant conjugates used to test the ability of eight experimental adjuvants and six different vehicles for enhancing antibody responses to the peptides in inbred strains of mice (C3H/He, C57BL/6, DBA/1, and SJL) and outbred rabbits. Antibody levels reactive to both 125 I‐peptides and 125 I‐HCG were used as...