Neuroprotective naphthalene and flavan derivatives from Polygonum cuspidatum
Abstract
Ten naphthalene derivatives including two unusual glycosides possessing a naphthalene-fused piceid via a [C8'-O-C6-C5-C7']-trans-dihydrofuran ring, two flavan derivatives, as well as sixteen known phenolic compounds, were isolated from Polygonum cuspidatum. The structures were determined by extensive NMR, MS, CD data, and chemical evidence. In the in vitro neuroprotective assays, at the concentration of 10 μM, five of these compounds exhibited...
Paper Details
Title
Neuroprotective naphthalene and flavan derivatives from Polygonum cuspidatum
Published Date
Feb 1, 2015
Journal
Volume
110
Pages
150 - 159
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