Chromosome stability, DNA recombination and the BRCA2 tumour suppressor
Abstract
The BRCA2 tumour suppressor works in DNA recombination and repair pathways to preserve genome integrity. Recent progress provides fresh insights into its role as a regulator of the Rad51 recombination protein, underpinning a model in which BRCA2's involvement in chromosome stability and tumour suppression arises from its participation in recombinational processes essential for DNA...
Paper Details
Title
Chromosome stability, DNA recombination and the BRCA2 tumour suppressor
Published Date
Jun 1, 2001
Volume
13
Issue
3
Pages
338 - 343
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