Putative role of proteolysis and in?ammatory response in the toxicity of nerve and blister chemical warfare agents: implications for multi-threat medical countermeasures

Volume: 23, Issue: 3, Pages: 177 - 186
Published: Jan 1, 2003
Abstract
Despite the contrasts in chemistry and toxicity, for blister and nerve chemical warfare agents there may be some analogous proteolytic and inflammatory mediators and pathological pathways that can be pharmacological targets for a single-drug multi-threat medical countermeasure. The dermal–epidermal separation caused by proteases and bullous diseases compared with that observed following exposure to the blister agent sulfur mustard...
Paper Details
Title
Putative role of proteolysis and in?ammatory response in the toxicity of nerve and blister chemical warfare agents: implications for multi-threat medical countermeasures
Published Date
Jan 1, 2003
Volume
23
Issue
3
Pages
177 - 186
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