Detection of sentinel nodes by a novel red-fluorescent dye, ATX-S10Na (II), in an orthotopic xenograft rat model of human gastric carcinoma

Background and Objective We developed a new imaging system to detect sentinel nodes (SNs) using a novel fluorescent tracer, ATX‐S10Na(II), and investigated its usefulness in an animal model. Study Design/Materials and Methods Human gastric carcinoma cells were implanted orthotopically into nude rats. ATX‐S10Na(II) was injected subserosally into the primary tumor lesion, and visualized by a fluorescence spectro‐laparoscope. Presence of tumor...