Novel action of activin and bone morphogenetic protein in regulating aldosterone production by human adrenocortical cells.

Volume: 145, Issue: 2, Pages: 639 - 649
Published: Feb 1, 2004
Abstract
We have uncovered a functional bone morphogenetic protein (BMP) and activin system complete with ligands (BMP-6 and activin betaA/betaB), receptors (activin receptor-like kinase receptors 2, 3, and 4; activin type-II receptor; and BMP type-II receptor), and the binding protein follistatin in the human adrenocortical cell line H295R. Administration of activin and BMP-6 to cultures of H295R cells caused concentration-responsive increases in...
Paper Details
Title
Novel action of activin and bone morphogenetic protein in regulating aldosterone production by human adrenocortical cells.
Published Date
Feb 1, 2004
Volume
145
Issue
2
Pages
639 - 649
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