Nutritional Flavonoids Modulate Estrogen Receptor α Signaling
Abstract
Estrogen receptor α (ERα) mediates 17β‐estradiol (E2) actions through the transcription of E2‐sensitive target genes. In addition, rapid non‐genomic signaling (e.g., MAPK/ERK) occurs. It is now well accepted that these rapid membrane‐initiated responses account for E2‐related cancer. Beside many beneficial effects on human health, nutritional flavonoids exert protective and anticarcinogenic effects on E2‐related cancer. The mechanism underlying...
Paper Details
Title
Nutritional Flavonoids Modulate Estrogen Receptor α Signaling
Published Date
Mar 1, 2004
Journal
Volume
56
Issue
3
Pages
145 - 151
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