Detection of proximal colorectal cancers through analysis of faecal DNA
Abstract
Detection of mutations in faecal DNA represents a promising, non-invasive approach for detecting colorectal cancers in average-risk populations. One of the first practical applications of this technology involves the examination of microsatellite markers in sporadic cancers with mismatch-repair deficiencies. Since such cancers nearly always occur in the proximal colon, this test might be useful as an adjunct to sigmoidoscopy, which detects only...
Paper Details
Title
Detection of proximal colorectal cancers through analysis of faecal DNA
Published Date
Feb 1, 2002
Journal
Volume
359
Issue
9304
Pages
403 - 404
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