Low-dose CT angiography: sufficient contrast for vessel imaging?

At present, noninvasive CT angiography has been shown to be as accurate as conventional angiography, and it had been presaged that CT angiography will soon be able to replace conventional coronary angiography [1–21]. The ACCURACY trial showed in 230 patients a 99% negative predictive value for CT angiography, establishing this method as an effective noninvasive alternative to conventional angiography to rule out obstructive coronary artery...