Platelets and matrix metalloproteinases
Abstract
Summary Matrix metalloproteinases (MMPs) and their inhibitors essentially contribute to a variety of pathophysiologies by modulating cell migration, tissue degradation and inflammation. Platelet-associated MMP activity appears to play a major role in these processes. First, platelets can concentrate leukocyte-derived MMP activity to sites of vascular injury by leukocyte recruitment. Second, platelets stimulate MMP production in e.g. leukocytes,...
Paper Details
Title
Platelets and matrix metalloproteinases
Published Date
Jan 1, 2013
Journal
Volume
110
Issue
11
Pages
903 - 909
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Notes
History