CCAAT/Enhancer binding protein β controls androgen-deprivation-induced senescence in prostate cancer cells
Abstract
The processes associated with transition to castration-resistant prostate cancer (PC) growth are not well understood. Cellular senescence is a stable cell cycle arrest that occurs in response to sublethal stress. It is often overcome in malignant transformation to confer a survival advantage. CCAAT/Enhancer Binding Protein (C/EBP) β function is frequently deregulated in human malignancies and interestingly, androgen-sensitive PC cells express...
Paper Details
Title
CCAAT/Enhancer binding protein β controls androgen-deprivation-induced senescence in prostate cancer cells
Published Date
Mar 16, 2015
Journal
Volume
34
Issue
48
Pages
5912 - 5922
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