A Potential Role for F-18 FDG PET/CT in Evaluation and Management of Fibrosing Mediastinitis.

Published on Sep 1, 2007in Clinical Nuclear Medicine6.587
· DOI :10.1097/RLU.0B013E318125035B
Amol Takalkar11
Estimated H-index: 11
Gabriel L. Bruno2
Estimated H-index: 2
+ 3 AuthorsD Keith Payne1
Estimated H-index: 1
Abstract: Fibrosing mediastinitis is an uncommon benign disorder, and its pathogenesis and management remain unclear. Conventional imaging techniques (chest radiographs, CT, MRI) may suggest its diagnosis but are frequently nonspecific, and it frequently mimics a malignant process by presenting as a mediastinal mass without calcifications, encasing, and infiltrating adjacent mediastinal structures, and showing an overall aggressive behavior. The value of FDG PET imaging in this entity remains largely unknown with only a few case reports in the literature, and often, biopsy is necessary for definitive diagnosis. We report a case of biopsy proven fibrosing mediastinitis highlighting the utility of PET in the evaluation and management of the disease.
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