Bioactive Polyprenylated Acylphloroglucinol Derivatives from Hypericum cohaerens
Abstract
Nine new polyprenylated acylphloroglucinol derivatives, hypercohins B-J (1-9), and nine known analogues were isolated from the aerial parts of Hypericum cohaerens. The structures of 1-9 were elucidated based on spectroscopic analysis, and the absolute configuration of 1 was confirmed by X-ray crystallographic analysis. The inhibitory activities of these isolates on acetylcholinesterase and five human tumor cell lines were tested, and hypercohins...
Paper Details
Title
Bioactive Polyprenylated Acylphloroglucinol Derivatives from Hypericum cohaerens
Published Date
Aug 19, 2013
Journal
Volume
76
Issue
9
Pages
1612 - 1618
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