Pulsatile Hormonal Signaling to Extracellular Signal-regulated Kinase

Volume: 289, Issue: 11, Pages: 7873 - 7883
Published: Mar 1, 2014
Abstract
Gonadotropin-releasing hormone (GnRH) is secreted in brief pulses that stimulate synthesis and secretion of pituitary gonadotropin hormones and thereby mediate control of reproduction. It acts via G-protein-coupled receptors to stimulate effectors, including ERK. Information could be encoded in GnRH pulse frequency, width, amplitude, or other features of pulse shape, but the relative importance of these features is unknown. Here we examine this...
Paper Details
Title
Pulsatile Hormonal Signaling to Extracellular Signal-regulated Kinase
Published Date
Mar 1, 2014
Volume
289
Issue
11
Pages
7873 - 7883
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