Ganglion Cell Loss and Age-Related Visual Loss: A Cortical Pooling Analysis

To evaluate the ability of the cortical pooling model to predict the effects of random, mild ganglion cell loss, we compared the predictions of the model with the age-related loss and variability in achromatic and chromatic contrast sensitivity.The relative sensitivity to small (0.5 degrees ) and large (3.0 degrees ) stimuli was compared in older (mean = 67 years, n = 27) and younger (mean = 23 years, n = 32) adults. Contrast sensitivity for...