The scavenging of hydroxyl radical(•OH) by a prostacyclin analogue, taprostene

Volume: 91, Issue: 1, Pages: 29 - 38
Published: Apr 1, 1994
Abstract
A possible mechanism by which prostacyclin (PGI2) analogues provide beneficial effects including improved survival in shock experimentally induced by endotoxin, polytrauma or hypovolemia was studied. Since several studies have implicated oxygen free radical-mediated tissue damage, we investigated whether PGI2-analogues exert their 'cytoprotective' effects by inhibiting overproduction of oxygen free radicals. For this reason, the efficiency of...
Paper Details
Title
The scavenging of hydroxyl radical(•OH) by a prostacyclin analogue, taprostene
Published Date
Apr 1, 1994
Volume
91
Issue
1
Pages
29 - 38
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