Impact of mean rectal dose on late rectal bleeding after conformal radiotherapy for prostate cancer: Dose–volume effect

Purpose To identify the clinical and dosimetric factors predictive of a greater risk of Grade 2 or worse late rectal bleeding in patients with localized prostate cancer treated with three-dimensional conformal radiotherapy in a prospective dose-escalation study. Methods and materials We performed a retrospective analysis of the clinical records and dose–volume histograms of 107 patients with Stage T1c-T3 prostate cancer treated at our...