Impact of cholesterol lowering treatment on plasma kynurenine and tryptophan concentrations in chronic kidney disease: Relationship with oxidative stress improvement

Volume: 25, Issue: 2, Pages: 153 - 159
Published: Feb 1, 2015
Abstract
Tryptophan (Trp) degradation via indoleamine (2,3)-dioxygenase (IDO), with consequent increased in kynurenine (Kyn) concentrations, has been proposed as marker of immune system activation. Oxidative stress (OS) might contribute to the pro-inflammatory state in chronic kidney disease (CKD) through the activation of NF-kB, with consequent activation and recruitment of immune cells.Serum concentrations of Trp and Kyn, oxidative stress indices...
Paper Details
Title
Impact of cholesterol lowering treatment on plasma kynurenine and tryptophan concentrations in chronic kidney disease: Relationship with oxidative stress improvement
Published Date
Feb 1, 2015
Volume
25
Issue
2
Pages
153 - 159
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