Functional gastrointestinal disorders and mast cells: implications for therapy.
Abstract
The pathophysiology of functional gastrointestinal disorders is poorly understood. Accepted common mechanisms include psychosocial factors, abnormal gastrointestinal motility and disturbed visceral sensory perception, but the underlying causes remain unclear. Mast cells (MCs) are immunocytes widely distributed throughout the gastrointestinal tract. Several stimuli (e.g. allergens, neuropeptides and stress) lead to MC activation with consequent...
Paper Details
Title
Functional gastrointestinal disorders and mast cells: implications for therapy.
Published Date
Jan 1, 2006
Volume
18
Issue
1
Pages
6 - 17
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