Cell proliferation and modulation of interaction of estrogen receptors with coregulators induced by ERα and ERβ agonists
Volume: 143, Pages: 376 - 385
Published: Sep 1, 2014
Abstract
The aim of the present study was to investigate modulation of the interaction of the ERα and ERβ with coregulators in the ligand responses induced by estrogenic compounds. To this end, selective ERα and ERβ agonists were characterized for intrinsic relative potency reflected by EC50 and maximal efficacy towards ERα and ERβ mediated response in ER selective reporter gene assays, and subsequently tested for induction of cell proliferation in...
Paper Details
Title
Cell proliferation and modulation of interaction of estrogen receptors with coregulators induced by ERα and ERβ agonists
Published Date
Sep 1, 2014
Volume
143
Pages
376 - 385
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