Immunomagnetic quantification of circulating tumor cells in patients with urothelial cancer

Objectives: To evaluate the relationship between circulating tumor cells (CTC) and clinical parameters in metastatic urothelial cancer (UC). Methods: CTC were enumerated with the CellSearch System, which was developed using an EpCAM antibody‐based immunomagnetic capture and automated staining methodology. UC cell lines (RT4, T24, TCC, UMUC3 and 253J) and mixed blood from healthy males were analyzed. Blood samples from 16 patients without...