DNA self-assembly: prospectus and its future application

Published on Jan 26, 2010in Journal of Materials Science4.22
· DOI :10.1007/S10853-010-4237-6
Sathya Sadhasivam5
Estimated H-index: 5
,
Kyusik Yun26
Estimated H-index: 26
Sources
Abstract
The field of DNA nanotechnology has grown rapidly in the past 10 years, with many baby steps and exciting breakthroughs. DNA has recently been emerged as a versatile material for constructing artificial molecular structures and strategy which has excellent intrinsic characteristics, including programmability, self-organization, molecular recognition, and molecular-scale structuring properties, makes it an attractive nanoscale building material. Excitingly, DNA can be considered as a natural candidate for molecular self-assembly. In this review, we have focused on the methods for DNA self assembling patterns within the molecular fabric of DNA lattices.
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References89
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DNA has proved to be a versatile building block in the creation of complex structures through self-assembly, exploiting the intermolecular forces between the components. Here, the arrangement of DNA helices on pleated strands which are then assembled into honeycomb-like three-dimensional structures, produces objects of unprecedented complexity.
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Molecular self-assembly strategies involve the formation of nanometer scale objects and materials in the absence of significant external control. One increasingly popular self-assembly approach makes use of the unique properties of deoxyribonucleic acid (DNA) including its diminutive size and high capacity for information storage. For many applications, DNA stands alone as the top choice for the programmable construction of supramolecular materials due to its specific and well-understood base-pa...
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The assembly of nanoparticles into three-dimensional (3D) architectures could allow for greater control of the interactions between these particles or with molecules. DNA tubes are known to form through either self-association of multi-helix DNA bundle structures or closing up of 2D DNA tile lattices. By the attachment of single-stranded DNA to gold nanoparticles, nanotubes of various 3D architectures can form, ranging in shape from stacked rings to single spirals, double spirals, and nested spi...
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