Platelet‐poor plasma stimulates the proliferation but inhibits the differentiation of rat osteoblastic cells in vitro

Recent studies have shown that the use of platelet preparations in bone and implant surgery might stimulate bone formation. However, the biological mechanisms are not well understood. Moreover, few studies have attempted to evaluate the effect of platelet-poor plasma (PPP), which is a product of the platelet-rich plasma preparation process.Thus, this study investigated the behavior of osteoblasts isolated from fetal rat calvaria cultivated in...