Intravitreal Triamcinolone for the Treatment of Ischemic Macular Edema Associated With Branch Retinal Vein Occlusion

Published on May 1, 2006in American Journal of Ophthalmology4.013
· DOI :10.1016/J.AJO.2005.12.011
Simon D.M. Chen15
Estimated H-index: 15
Venki Sundaram3
Estimated H-index: 3
+ 1 AuthorsChetan K. Patel23
Estimated H-index: 23
Purpose To evaluate the safety and efficacy of intravitreal triamcinolone acetonide (IVTA) for ischemic macular edema associated with branch retinal vein occlusion (BRVO) and foveal ischemia. Design Prospective interventional case series. Methods setting: Clinical practice. study population: Eighteen eyes of 18 patients with macular edema associated with BRVO and foveal ischemia. intervention: Four mg IVTA. main outcome measures: Visual acuity (VA), optical coherence tomography, macular thickness measurements, and treatment-related complications. Results The mean duration of BRVO before treatment was 14 months. All patients were followed for a minimum of nine months, and 12 patients completed 12 months follow-up. The mean logarithm of the minimum angle of resolution (logMAR) VA improved significantly from 0.81 ± 0.36 at baseline to 0.65 ± 0.30 at one month ( P = .03) but did not vary significantly from baseline at three, six, nine, and 12 months. Macular thickness improved significantly in all eyes from a mean of 400 ± 134 μm preinjection, to 228 ± 58 μm at one month ( P P Conclusions IVTA is effective in reducing ischemic macular edema associated with BRVO and foveal capillary nonperfusion. This reduction is often associated with a temporary improvement in VA. Raised IOP and development of posterior subcapsular cataract are disadvantages of this treatment.
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