CD86 Polymorphism Affects Pneumonia-Induced Sepsis by Decreasing Gene Expression in Monocytes
Abstract
Sepsis, a clinical syndrome occurring in patients following infection or injury, is a leading cause of morbidity and mortality worldwide. CD86 (B7-2) is a costimulatory molecule on antigen-presenting cells and plays critical roles in immune responses. In the current study, we investigated the association of two CD86 polymorphisms, rs1129055G/A and rs17281995G/C, with susceptibility to pneumonia-induced sepsis and examined the effects of these...
Paper Details
Title
CD86 Polymorphism Affects Pneumonia-Induced Sepsis by Decreasing Gene Expression in Monocytes
Published Date
Aug 17, 2014
Journal
Volume
38
Issue
2
Pages
879 - 885
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