Multi-organ injuries caused by lipopolysaccharide-induced periodontal inflammation in rats: role of melatonin

Background and Objective Periodontitis, a chronic inflammatory disease caused by oral bacterial infection, is considered to be a risk factor for systemic diseases including diabetes mellitus, bacterial pneumonia, hyperlipidemia and atherosclerosis. The aim of this study was to evaluate the effectiveness of melatonin against periodontal inflammation‐induced multiple organ injury in rats. Material and Methods Eighteen female Wistar albino rats...