FC‐27 A spontaneous dog model for in vivo gene therapy of junctional epidermolysis bullosa

Volume: 15, Pages: 29 - 29
Published: Aug 1, 2004
Abstract
Junctional epidermolysis bullosa (JEB) is a mechanobullous skin disease associated with mutations in the basement membrane components of the dermo-epidermal junction. This condition is a suitable prototype for proving the feasibility of a gene therapy approach to genodermatoses. As successful genetic treatment requires immunocompetent animal models to study the possible host immune response to the transgene, we have characterized a breed of...
Paper Details
Title
FC‐27 A spontaneous dog model for in vivo gene therapy of junctional epidermolysis bullosa
Published Date
Aug 1, 2004
Volume
15
Pages
29 - 29
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