Silver Succinylsulfadiazine and Silver Sulfadiazine Imidazole: Two New Derivatives of the Antibacterial Silver Sulfadiazine
Abstract
Because of the low water solubility of silver sulfadiazine (0.34 mg/100 ml) the preparation of more soluble derivatives has been studied. One such derivative was prepared by the introduction of a succinyl group on the aromatic amino group of sulfadiazine. The silver compound had the composition Ag2(succinylsulfadiazine). The water solubility of this compound with respect to silver sulfadiazine was enhanced by the factor 2 for [sulfanilamide] and...
Paper Details
Title
Silver Succinylsulfadiazine and Silver Sulfadiazine Imidazole: Two New Derivatives of the Antibacterial Silver Sulfadiazine
Published Date
Jan 1, 1980
Journal
Volume
313
Issue
12
Pages
1016 - 1020
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