RSK2 regulates endocytosis of FGF receptor 1 by phosphorylation on serine 789

Volume: 33, Issue: 40, Pages: 4823 - 4836
Published: Oct 21, 2013
Abstract
FGFR1 (fibroblast growth factor receptor 1) regulates many key cellular responses including proliferation, migration and differentiation through activation of signaling pathways. Irregularities in FGFR1 signaling have been implicated in several pathological conditions, including human cancer. In order to discover novel regulators of FGFR1 signaling, we performed yeast two-hybrid screens and identified RSK2 (p90 ribosomal S6 kinase 2) as a...
Paper Details
Title
RSK2 regulates endocytosis of FGF receptor 1 by phosphorylation on serine 789
Published Date
Oct 21, 2013
Journal
Volume
33
Issue
40
Pages
4823 - 4836
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