A Randomized Prospective Multicenter Trial of Pancreaticoduodenectomy With and Without Routine Intraperitoneal Drainage

In Brief Objective: To test by randomized prospective multicenter trial the hypothesis that pancreaticoduodenectomy (PD) without the use of intraperitoneal drainage does not increase the frequency or severity of complications. Background: Some surgeons have abandoned the use of drains placed during pancreas resection. Methods: We randomized 137 patients to PD with (n = 68, drain group) and without (n = 69, no-drain group) the use of...