N-cadherin antagonists as oncology therapeutics

Volume: 370, Issue: 1661, Pages: 20140039 - 20140039
Published: Feb 5, 2015
Abstract
The cell adhesion molecule (CAM), N-cadherin, has emerged as an important oncology therapeutic target. N-cadherin is a transmembrane glycoprotein mediating the formation and structural integrity of blood vessels. Its expression has also been documented in numerous types of poorly differentiated tumours. This CAM is involved in regulating the proliferation, survival, invasiveness and metastasis of cancer cells. Disruption of N-cadherin homophilic...
Paper Details
Title
N-cadherin antagonists as oncology therapeutics
Published Date
Feb 5, 2015
Volume
370
Issue
1661
Pages
20140039 - 20140039
Citation AnalysisPro
  • Scinapse’s Top 10 Citation Journals & Affiliations graph reveals the quality and authenticity of citations received by a paper.
  • Discover whether citations have been inflated due to self-citations, or if citations include institutional bias.