Urinary tract infections: epidemiology, mechanisms of infection and treatment options

Urinary tract infections (UTIs) pose a severe public health problem and are caused by a range of pathogens. In this Review, Hultgren and colleagues discuss how basic science studies are elucidating the molecular mechanisms of UTI pathogenesis and how this knowledge is being used for the development of novel clinical treatments for UTIs. Urinary tract infections (UTIs) are a severe public health problem and are caused by a range of pathogens, but...