Continuous cultures of fused cells secreting antibody of predefined specificity
Abstract
THE manufacture of predefined specific antibodies by means of permanent tissue culture cell lines is of general interest. There are at present a considerable number of permanent cultures of myeloma cells1,2 and screening procedures have been used to reveal antibody activity in some of them. This, however, is not a satisfactory source of monoclonal antibodies of predefined specificity. We describe here the derivation of a number of tissue culture...
Paper Details
Title
Continuous cultures of fused cells secreting antibody of predefined specificity
Published Date
Aug 1, 1975
Journal
Volume
256
Issue
5517
Pages
495 - 497
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