Propranolol as a First-line Treatment for Diffuse Infantile Hepatic Hemangioendothelioma

Hepatic tumors are uncommon in the neonatal period, and of those infantile hepatic hemangioendotheliomas (IHHs) are the most frequently occurring primary hepatic lesions (1). They are divided into 3 main groups—focal, multifocal, and diffuse. Seventy-five percent of the diffuse tumors are associated with hemangiomas in other organs, with almost half presenting with cutaneous hemangiomas (1). Observation is recommended for focal lesions, whereas...