Encapsulated islets for diabetes therapy: History, current progress, and critical issues requiring solution
Abstract
Insulin therapy became a reality in 1921 dramatically saving lives of people with diabetes, but not protecting them from long-term complications. Clinically successful free islet implants began in 1989 but require life long immunosuppression. Several encapsulated islet approaches have been ongoing for over 30 years without defining a clinically relevant product. Macro-devices encapsulating islet mass in a single device have shown long-term...
Paper Details
Title
Encapsulated islets for diabetes therapy: History, current progress, and critical issues requiring solution
Published Date
Apr 1, 2014
Volume
67-68
Pages
35 - 73
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Notes
History