Blood markers of early and late airway responses to allergen in asthmatic subjects. Relationship with functional findings.
Abstract
We evaluated the relationship between blood markers of mast-cell (plasma histamine and serum level of heat-stable neutrophil chemotactic activity [NCA]) and eosinophil (serum eosinophil cationic protein [ECP]) activation during early airway response (EAR) and late airway response (LAR) to allergen inhalation in 24 asthmatic subjects. After EAR, 14 subjects showed significant LAR (FEV1 fall: > or = 25%), while 10 subjects showed equivocal LAR...
Paper Details
Title
Blood markers of early and late airway responses to allergen in asthmatic subjects. Relationship with functional findings.
Published Date
Jan 1, 1997
Journal
Volume
52
Issue
1
Pages
32 - 40
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Notes
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