Ketamine Attenuates Delirium After Cardiac Surgery With Cardiopulmonary Bypass

Objective To determine if ketamine attenuates postoperative delirium concomitant with an anti-inflammatory effect in patients undergoing cardiac surgery using cardiopulmonary bypass. Design A prospective randomized study. Setting A Veterans Affairs medical center. Participants Cardiac surgical patients. Interventions Patients at least 55 years of age randomly received placebo (0.9% saline, n = 29) or an intravenous bolus of ketamine (0.5 mg/kg...