Comparative pharmacokinetics of puerarin, daidzin, baicalin, glycyrrhizic acid, liquiritin, berberine, palmatine and jateorhizine by liquid chromatography–mass spectrometry after oral administration of Gegenqinlian decoction and active components alignment (ACA) to rats
Abstract
An LC–MS/MS method was developed for simultaneous analysis of puerarin, daidzin, baicalin, glycyrrhizic acid, liquiritin, berberine, palmatine and jateorhizine of Gegenqinlian Decoction (GQD) and active components alignment (ACA) in rat plasma using hesperidin as the internal standard (I.S.). Chromatography was performed using a C18 column, with gradient elution with 1% acetic acid–0.001 mol/L ammonium acetate and acetonitrile at 0.2 ml/min. All...
Paper Details
Title
Comparative pharmacokinetics of puerarin, daidzin, baicalin, glycyrrhizic acid, liquiritin, berberine, palmatine and jateorhizine by liquid chromatography–mass spectrometry after oral administration of Gegenqinlian decoction and active components alignment (ACA) to rats
Published Date
Apr 1, 2015
Journal
Volume
988
Pages
33 - 44
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