Urinary leukotriene E4 and 9alpha, 11beta-prostaglandin F2 concentrations in mild, moderate and severe asthma, and in healthy subjects

Summary Background Airway inflammation in asthma is associated with cysteinyl leukotriene and prostaglandin D 2 production. Measurement of urinary metabolites of these eicosanoids may be useful for monitoring asthma patients. However, the influence of asthma phenotype and severity on basal urinary excretion of these metabolites is unknown. Objective To compare urinary leukotriene (LT)E 4 and 9α, 11β‐prostaglandin (PG)F 2 concentrations in large...