TRPC1 Channels Are Critical for Hypertrophic Signaling in the Heart

Volume: 105, Issue: 10, Pages: 1023 - 1030
Published: Nov 6, 2009
Abstract
Rationale: null null Cardiac muscle adapts to increase workload by altering cardiomyocyte size and function resulting in cardiac hypertrophy. G protein–coupled receptor signaling is known to govern the hypertrophic response through the regulation of ion channel activity and downstream signaling in failing cardiomyocytes. null null null Objective: null null Transient receptor potential canonical (TRPC) channels are G protein–coupled receptor...
Paper Details
Title
TRPC1 Channels Are Critical for Hypertrophic Signaling in the Heart
Published Date
Nov 6, 2009
Volume
105
Issue
10
Pages
1023 - 1030
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