Berberine protects homocysteic acid-induced HT-22 cell death: involvement of Akt pathway

Volume: 30, Issue: 1, Pages: 137 - 142
Published: Jul 23, 2014
Abstract
Berberine (BBR), one of the major constituents of Chinese herb Rhizoma coptidis, has been reported to exert beneficial effects to various diseases, including Alzheimer's disease (AD). In the present work, we aimed to investigate the effects of BBR on neuronal cell death induced by homocysteic acid (HCA), which was considered as a risk of AD. BBR significantly reduced HCA-induced reactive oxygen species (ROS) generation, lactate dehydrogenase...
Paper Details
Title
Berberine protects homocysteic acid-induced HT-22 cell death: involvement of Akt pathway
Published Date
Jul 23, 2014
Volume
30
Issue
1
Pages
137 - 142
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