Understanding quantitative pulsed CEST in the presence of MT

Phantom experiments in agar and ammonium chloride were performed to evaluate a three‐pool model of magnetization transfer and chemical exchange saturation transfer (CEST) in a pulsed saturation transfer experiment. The utility of the pulsed CEST method was demonstrated by varying the pH of the phantoms and observing the effect upon the CEST spectra both with and without the solid agar (the magnetization transfer pool), while fitting the spectra...