A method for estimating the solvent strength parameter in liquid-solid chromatography

The intermolecular interactions responsible for the adsoprtion of solvents on alumina and silica are chracterized using the solvation parameter model. Both adsorbents retain solvents by strong hydrogen bond and dipole-type interactions. alumina is significantly more hydrogenbond basic and less hydrogen-bond acidic than silica, while both adsorbents are reasonably dipolar/polarizable. Increasing solvent size reduces polar adsorbent interactions....