Inhibition of death receptor signaling by bacterial gut pathogens
Abstract
Gastrointestinal bacterial pathogens such as enteropathogenic Escherichia coli, Salmonella and Shigella control inflammatory and apoptotic signaling in human intestinal cells to establish infection, replicate and disseminate to other hosts. These pathogens manipulate host cell signaling through the translocation of virulence effector proteins directly into the host cell cytoplasm, which then target various signaling pathways. Death receptors...
Paper Details
Title
Inhibition of death receptor signaling by bacterial gut pathogens
Published Date
Apr 1, 2014
Volume
25
Issue
2
Pages
235 - 243
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History