Substance-p-mobilized mesenchymal stem cells accelerate skin wound healing

Mesenchymal stem cells (MSCs) exert their therapeutic effects through differentiation into a variety of terminally differentiated cells or the release of paracrine factors. As a source for obtaining MSC, bone marrow has been used chiefly but the exploit of adipose tissue, dental pulp and peripheral blood is also increasing. Previous reports demonstrated that SP mobilizes bone marrow MSC to the circulation to be engaged in tissue repair....