Investigation and management of heritable thrombophilia

There is no internationally accepted definition of thrombophilia. The British Committee for Standards in Haematology (1990) suggested that the term thrombophilia be used to describe ‘disorders of the haemostatic mechanisms which are likely to predispose to thrombosis’. This definition is widely used but has disadvantages. Firstly, as new thrombophilic conditions have been described, it has become evident that many individuals who carry these...